One repulsive term unlocked hidden protein shapes.

Proteins do their job by changing shape, not by holding one.

Researchers at Japan’s Institute for Molecular Science pushed predictions away from prior answers to force new ones.

The fix suggests other generative models could gain similar diversity training.

How each outlet framed it
Phys.org
describes repulsive force bias method enabling AlphaFold3 to sample protein conformations it normally misses

Sources: Phys.org