TempeResearchers mapped DNA methylation across 864 dogs.
Large breeds die younger, the reverse of the pattern across mammal species.
Ageing is linked to lost methylation marks on LINE1 jumping genes, which can copy themselves across the genome and damage DNA.
The study, published in Science, draws on the Dog Aging Project.
Arizona State University’s Noah Snyder-Mackler says dog findings can translate to human health.
How each outlet framed it
- Phys.org
- emphasizes molecular mechanism—Arizona State study shows hallmarks of aging reshape dog DNA, frames as window into human aging biology
Sources: Phys.org