United KingdomThe peptide LL-37 kills bacteria better at fever temperature.

Fever raises antibacterial killing yet limits mitochondrial damage when no pathogen is present, the study finds.

Peptides from other animals have temperature sensitivities tuned to their body temperatures, and cold-blooded animals avoid mitochondrial damage another way.

Whether suppressing fever with antipyretics blunts the effect in patients, the abstract does not say.

How each outlet framed it
Nature Communications
argues fever's benefit is tuned to body temperature, with warm-blooded animals raising LL-37 killing efficacy while limiting mitochondrial damage

Sources: Nature Communications