Moscow630 drones headed for the region overnight, mayor Sergei Sobyanin said.
Sobyanin called it the largest drone attack on the capital this year.
Air defences shot most down far from the regional border, he said, and 163 as they approached Moscow.
Two people were injured in the Voronovo district, Sobyanin said.
Days earlier, Ukraine’s president Volodymyr Zelensky floated freezing the front before November talks with Vladimir Putin.
Sources: Adnkronos