PittsburghNearly 100,000 Americans revealed thousands of new drug-response gene variants.

Variants can change doses, add side effects or disable drugs including Plavix and statins.

The study, in Science Translational Medicine, drew on more diverse ancestries than databases like the UK Biobank.

Senior author Philip Empey names barriers: few sequenced genomes and physicians unaware which drugs variants affect.

All of Us expects $122 million once Congress sets a budget, 80% below its 2023 peak.

How each outlet framed it
STAT
reports the study's diversity point: ~100,000 Americans from more varied ancestries, so the pharmacogene variants found are not limited to European-ancestry samples

Sources: STAT